· Fresh material: 60 to 260 gms, dried material: 30 to 60 gms: Take in form of decoction.
· Counterirritant: Pound fresh leaves, mix with vaseline or oil and apply over affected area as poultice.
• Wounds and sore: The sap of the leaves is used on wounds and skin sores.
• In many folkloric systems, used for tuberculosis, syphilis, dysentery, hypertension, venous extremity probolems and common cold.
· In India and Fiji, roots used forskin inflammation, to improve blood circulation, to treat bloating, congestion and depression.
· Also considered to be a brain and memory stimulant, used for Alzheimer's disease and senility.
• In Ayurvedic and Chinese medicine, used for depression and anxiety.
• In Sri Lanka and Madagascar, used for a variety of mental and neurological problems.
• Anxiolytic: Rat studies have shown decrease in locomotor activity, enhanced maze performance and attenuated started response. This placebo- controlled studysuggest Gotu Kola has anxiolytic activity in humans as shown by the ASR (acoustic startle response).
• Bactericidal: In vitro study on the effect of CA on enteric pathogens. The alchol extract was bactericidal against V cholera, Shigella spp, and Staph aureus and suggests further studies in its potential as an antidiarrheal drug.
• Wound Healing: Study on albino rats showed the leaf extract of CA significantly promoted wound healing and was able to overcome the wound-healing suppression of dexamethasone.
• Antioxidant: Study showed CA extract and power may ameliorate H202-induced oxidative stress by decreasing lipid peroxidation.
• Immunomodulatory: Study revealed immunomodulatory activity of C asiatica and R nasutus extracts in both non-specific cellular and humoral immune responses. Results suggest a chemoproventive or anticancer potential.
• Nerve Regeneration: Study indicates components in CA ethanolic extract may be beneficial for accelerating repair of damaged neurons.
• Scleroderma: Single study found gotu kola decreased joint pain and skin hardening and improved finger movement. source
• Periodontal Healing : Study results indicate that the combined use of extracts of CA and P granatum pericarp significantly reduced the clinical signs of chronic periodontitis.
• Larvicidal: Crude extract of leaves of CA showed larvicidal and adult emergence inhibition against mosquite Cules quinquefasciatus, possibly through various biogically active compounds–phenolics, terpenoids and alkaloids.